The GB viruses: a review and proposed classification of GBV-A, GBV-C (HGV), and GBV-D in genus Pegivirus within the family Flaviviridae

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The GB viruses: a review and proposed classification of GBV-A, GBV-C (HGV), and GBV-D in genus Pegivirus within the family Flaviviridae

In 1967, it was reported that experimental inoculation of serum from a surgeon (G.B.) with acute hepatitis into tamarins resulted in hepatitis. In 1995, two new members of the family Flaviviridae, named GBV-A and GBV-B, were identified in tamarins that developed hepatitis following inoculation with the 11th GB passage. Neither virus infects humans, and a number of GBV-A variants were identified...

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GBV-C/HGV and HIV-1 coinfection.

An interesting interaction pattern has been found between HIV-1 and GBV-C/HGV, resulting in protection against progression to AIDS. The mechanisms involved in this interaction remain to be clarified. We examined the current knowledge concerning this coinfection and developed hypotheses to explain its effects. A better understanding of this interaction could result in new concepts, which may lea...

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GBV-C/HGV infection in renal dialysis and transplant patients.

BACKGROUND Recently a new human virus (GBV-C/HGV) was identified. With the use of the polymerase chain reaction (PCR) the possibility of a high prevalence of the GBV-C/HGV infection in haemodialysis patients was demonstrated. The aim of the present study was to use a combination of the PCR and a new diagnostic test for antibodies to the viral envelope protein E2 to assess the prevalence of the ...

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Outcome of mother to infant acquired GBV-C/HGV infection.

Twelve children born to hepatitis C virus antibody GBV-C/HGV RNA positive mothers who acquired GBV-C/HGV infection by the vertical or perinatal route were studied. Most (91%) were persistently GBV-C/HGV RNA positive up to 12 months of age. Four out of six cases who acquired GBV-C/HGV alone had normal alanine amino transferase activities. Long lasting evidence of hepatocellular injury was detect...

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New Chimeric Porcine Coronavirus in Swine Feces, Germany, 2012

References 1. Stapleton JT, Bukh J, Muerhoff AS, Foung S, Simmonds P. Assignment of human, simian and bat pegiviruses (previously described as GBV-A, GBV-C, and GBV-D) as members of a new genus (Pegivirus) within the Flaviviridae [cited 2015 Oct 21]. http://www.ictvonline.org/proposals/2012.011a-dV.A.v2. Pegivirus.pdf 2. Thézé J, Lowes S, Parker J, Pybus OG. Evolutionary and phylogenetic analys...

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ژورنال

عنوان ژورنال: Journal of General Virology

سال: 2010

ISSN: 0022-1317,1465-2099

DOI: 10.1099/vir.0.027490-0